Islam needs us to make sacrifices for its sake. Just consider what  pure and virtuous lives have been sacrificed from the advent of Islam down to  the present time. A case in point is Hadrat Amir (Imam Ali) who fought against Muawiyah  for eighteen months in the Battle of Siffin, and who killed so many adversaries  and lost the lives of so many fellow combatants, over ten thousand people in  all, well over this figure. Muawiyah was someone who made claim to being Muslim  and to being the Prophet's rightful successor. He prayed at congregational  prayer gatherings, was the Friday prayer leader, and so on. He practiced all of  the outwardly visible religious practices. Unlike Yazid whose exterior was as  aberrant as his interior, Muawiyah was good at keeping up appearances. He kept  up appearances and also advocated Islam, so what actually happened to cause  Hadrat Amir to engage in battle against him? The reason Imam Ali fought against  Muawiyah was because he was a tyrant who had unfairly exploited the people. He  had seized Sham from Islamic rule and was forcing the people to behave  ruthlessly and to commit injustices. He plundered the people's wealth, the  public treasury. Hadrat Amir was obliged by duty to fight against him  irrespective of whether he was to be the vanquished or the vanquisher. The fact  that he may be defeated if he were to engage in battle at this time, did not  concern Hadrat Amir. Once he saw that he was able to confront Muawiyah in  battle, he rounded up his troops and battle commenced, although it is true to  say that on this particular occasion he was eventually defeated.
   
  Sahifeh, vol.4, Page: 140 
  Speech, October 25, 1978