Ashraf al-Qedra, the spokesman of Gaza Health Ministry, reported that Israeli forces attacked Palestinians on Friday. The wounded include three medics and a journalist.
The spokesman added that 82 of the injured were transferred to hospital.
A 10-year-old boy and a female medic, Shorouk Abu Mesameh, were in critical condition.
Tensions have been running high near the fence since March 30, which marked the start of a series of protests dubbed “The Great March of Return.” Palestinian protesters demand the right to return for those driven out of their homeland.
The clashes in Gaza reached their peak on May 14, the eve of the 70th anniversary of Nakba Day, or the Day of Catastrophe, which coincided this year with Washington's relocation of the US embassy from Tel Aviv to occupied Jerusalem al-Quds.
Israeli fire has taken the lives of more than 170 Palestinians since March 30.